Difference between Histone proteins and Non-histone proteins
Difference between Histone proteins and Non-histone proteins are in tabular form below –
No. |
Histone proteins |
Non-histone proteins |
Definition |
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1. | A unique group of proteins which are highly alkaline basic proteins and mainly found in the nuclei of eukaryotic cell, also it forms chromatin and DNA folding, this is known as Histone proteins. | A group of proteins which is heterogeneous group and plays role in regulation of gene expression, DNA replication, steroid hormone action, RNA processing and nucleosome remodelling, this is known as Non-histone proteins. |
Acidic or Basic |
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2. | The histone proteins are basic proteins. | The non-histone proteins are Acidic proteins. |
Proteins |
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3. | In the nucleus, histone proteins associate with DNA. | When the histones have been removed, remaining part is non-histone protein. |
Conservation |
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4. | These proteins are highly conserved. | These proteins are less conserved. |
Types |
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5. | In the histone proteins, type include H1, H2A, H3, H4 and H2B. | In the non-histone proteins, types include polycomb, scaffold proteins, heterochromatin protein and DNA polymerase. |
Functions |
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6. | This protein packages DNA into nucleosomes. | This protein regulates histone gene expression. |