Difference between Exonuclease and Endonuclease
Difference between Exonuclease and Endonuclease are in tabular form below –
No. |
Exonuclease |
Endonuclease |
Definition |
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1. | An enzyme which cleave nucleic acid at the middle and results in single nucleotide, this is referred to as Exonuclease. | An enzyme where it cleaves nucleic acid at the end and separates nucleotides other than the two end ones, this is referred to as Endonuclease. |
Enzyme act |
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2. | This enzyme acts on DNA which is single stranded. | This enzyme acts on the DNA which is double stranded. |
Nucleic acid cleave |
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3. | Here, nucleic acid gets cleave at the ends. | Here, nucleic acid gets cleave at the middle. |
DNA cleave |
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4. | This enzyme cleave at the end of the DNA. | This enzyme cleave within the DNA strands. |
Examples |
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5. | Example of exonuclease is snake venom. | Examples of endonucleases are restriction enzyme, EcoR1, DNases, and SI nuclease. |
Results |
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6. | In the exonuclease, nucleotides of single or nucleotides are shown in the results. | In the endonuclease, oligonucleotides are shown in the results. |